Medical Testing Laboratories
Biomarker Testing
Biomarker assays and readouts are important decision-making tools in drug discovery from target validation studies to candidate selection. Since biomarker assays are a component when studying mechanism, efficacy, bioavailability, liability, and safety considerations, the ability to measure with high accuracy and sensitivity is essential in making critical go/no-go study decisions.
Through its state of the art analytical and bioanalytical technology, JOINN’s Bioanalytical Lab Team offers biomarker method development, biomarker validation, and biomarker sample analysis serving for global pharmaceutical and biotechnology organizations.
Services
LC-MS/MS Biomarker Assays
Ligand Binding Biomarker Assays
Biomarker Method Development and Validation
Biomarker Sample Analysis
Biomarker
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Platform |
Indicators |
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Biochemical |
C3, C4, C-Reactive Protein (CRP), Immunoglobulin G (IgG), Immunoglobulin A (IgA), Immunoglobulin M (IgM), Immunoglobulin E (IgE), Creatine Kinase (CK), CK-MB, D-Dimer, Non-estesterified fatty acid (NEFA), Creatinine (CRE), α-Microglobulin (α1-MG), 25-hydroxy vitamin D (25-OH VD), Heart-type fatty acid binding protein(H-FABP), Glycated Serum Protein(GSP), Angiotensin-converting enzyme (ACE), β2-MG(BMG)…… |
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Immunoluminescence |
Follicle-Stimulating Hormone (FSH), Luteinizing Hormone (LH), Estradiol, Progesterone, Testosterone, Human Chorionic Gonadotropin+β-Subunit (HCG+β), Insulin, C-Peptide, Hydrocortisone, β-C-terminal telopeptide (β-CTx), Procollagen 1 Intact N-Terminal Propeptide (P1NP ), Alpha-fetoprotein (AFP)…… |
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Coagulation function |
Blood coagulation factor (II、V、VII、VIII、IX、X、XI、XII), Factor VIII inhibitor, Anti-Xa Assay，Prothrombin time (PT), Activated partialthromboplastin time (APTT), Fibrinogen (Fib), Thrombin time (TT), RT, Antiphospholipid antibodies (APA), Fibrin monomer (FM)…… |
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Flow cytometer |
TBNK cells（CD45、CD3、CD19、CD20、CD56、CD16）、Treg cells（CD25、CD127、Foxp3）、T lymphocyte subsets: naïve T cell, central memory T cell (Tcm), effector memory T cell (Tem, CD45RA、CD197), T cell activation（CD25、CD69、HLA-DR、CD38）, PD1+T cells（CD279）、B lymphocyte subsets：Memory B cells；Unswitched Memory B；Switched Memory B；Plasma cell PC （CD27、IgD、CD38、CD138）、Intracellular Cytokine Staining（IL-2、TNF-α、IFN-γCD40L）……… |
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MSD |
IL-2、IL-6、IL-8、IL-10、IL-12p70、IFN-γ、TNF-α，TGF-β1，SAA，PGE2，TGF-β1，VEGF-A，FGF21，CL2，Aβ38 (6E10)，Aβ40 (6E10)，Aβ42 (6E10)，GLP-1 (active)，Leptin，Complement C9，Tau (p181)，Tau (p217)，Tau (p231)，TSLP，Neurofilament L，GFAP…… |
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Simoa |
pTau-181，pTau-217，pTau-231，pTau-205，Tau，NF-light，TDP-43 |
