DIGESTIVE DISORDERS
|
Indication |
Model |
Species |
|
Acute gastric ulcer |
1. Water stress 2. Histamine induction 3. Ethanol induction 4. Pentagastrin induction 5. NSAID induction 6. Pylorus ligation |
rat |
|
Chronic gastric ulcer |
Acetic acid cauterization |
rat |
|
Acute and chronic liver injury/fibrosis |
CCl4 Induction |
rat, mice |
|
TAA Induction |
rat |
|
|
Bile duct ligation |
rat |
|
|
ConA Induction |
mice |
|
|
LPS+ D-GalN |
mice |
|
|
Hepatic fibrosis/Decompensated cirrhosis |
CCl4 + HFD + ethanol |
rat |
|
Nonalcoholic fatty liver disease (NASH) |
MCD-induced NASH |
mice |
|
CDAA + HFD-induced NASH |
mice |
|
|
GAN/ALMN diet-induced NASH |
mice |
|
|
ob/ob mice |
||
|
STZ + HFD-induced NASH |
newborn mice |
|
|
CCl4 + HFD |
rat |
|
|
HFHC diet-induced NASH |
cynomolgus monkey |
|
|
High Fructose Diet Induction |
Golden hamster |
